The cell cytoskeleton plays a key role in human biology and disease, contributing ubiquitously to such important processes as embryonic development, wound repair and cancer metastasis. The Papoian laboratory is interested in gaining deeper understanding of the physical chemistry behind these complex, far-from-equilibrium mechanochemical processes.
August 2018 - MEDYAN v3.2 is published. [Download]
April 2018 - Our paper titled Stochastic Ratcheting on a Funneled Energy Landscape Is Necessary for Highly Efficient Contractility of Actomyosin Force Dipoles was accepted in Phys Rev X.